Salbutamol sulphate or albuterol sulphate is used as a bronchodilator. This active ingredient is a β2 adrenergic receptor agonist which is used to treat bronchospasm in asthma. It is marketed as a suspension in a metered-dose inhaler (MDI). When salbutamol sulphate is inhaled, it causes bronchodilation in only a few minutes. After study of the drug, it became possible to develop a novel method which led to improvement of its galenic formulation. The new method would allow for smaller crystals with increased dimensional stability in comparison with the current one. Moreover, an industrial manufacturing process has been proposed, as well as quality control procedures for the new drug product, both in line with current legislation. The manufacturing process is one employing the cold-fill method. Finally, there is a design proposal for its packaging.